The maximum recommended daily dose is 60 mL (960 mg trimethoprim) per day. The dose of this medicine will be different for different patients. Yes, Bactrim is commonly used to treat UTIs. There are other medications that only cause red cell breakdown if taken in high doses. Septra and Bactrim (sulfamethoxazole-trimethoprim) are some common brand names you might encounter. Adults1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 5 days. Antibiotics (Bactrim) and Tattoos : r/tattoos - Reddit Bad infections may result in long-term antibiotic care, but usually they wont cause any long-lasting health problems. Avoid coadministration of BACTRIM with drugs that are substrates of CYP2C8 and 2C9 or OCT2. The Answer May Surprise You. Serious adverse reactions including fatal reactions and the gasping syndrome occurred in premature neonates and low birth weight infants in the neonatal intensive care unit who received benzyl alcohol as a preservative in infusion solutions. Dr. Hiep Le answered Nephrology and Dialysis 44 years experience PDF BACTRIM sulfamethoxazole and trimethoprim PEDIATRIC SUSPENSION DESCRIPTION Use Bactrim only as directed. But it can also trigger a hemolytic crisis in people with G6PD deficiency. The site is secure. In glucose-6-phosphate dehydrogenase deficient individuals, hemolysis may occur. BACTRIM is contraindicated in the following: BACTRIM is an antimicrobial drug [see Microbiology]. The average household teaspoon may not hold the right amount of liquid. Tell your doctor about any new medications youre taking. Last updated on March 1, 2023. Many other antibiotics are safe for people with G6PD deficiency. should have been 10 days but was having side effects. In general, you should do the following to make sure the area heals properly: Once the tattooed area starts to form into scabs, use a moisturizer or lotion to keep your skin from getting too dry or damaged. Antimicrob Agents Chemother. BACTRIM contains benzyl alcohol as a preservative. Over The Counter Antibiotics For Infected Tattoo - TattooTalk.net lower back or side pain. Signs of acute overdosage with trimethoprim include nausea, vomiting, dizziness, headache, mental depression, confusion and bone marrow depression. My Tattoo Itches and I Dont Want to Damage It, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI. (875 mg orally every 12 hours) plus either doxycycline (100 mg orally twice daily) or trimethoprim-sulfamethoxazole (TMP-SMX; one to two double-strength . Life threatening hyperkalemia and acidosis secondary to trimethoprimsulfamethoxazole treatment. Dieckmann R, Boone I, Brockmann SO, Hammerl JA, Kolb-Murer A, Goebeler M, Luch A, Al Dahouk S. Dtsch Arztebl Int. If you miss a dose of this medicine, take it as soon as possible. Remove the bandage 3 to 5 hours after youve gotten the tattoo. When culture and susceptibility information are available, they should be considered in selecting or modifying antibacterial therapy. Preterm, low-birth weight infants may be more likely to develop these reactions because they may be less able to metabolize benzyl alcohol. See additional information. You can learn more about how we ensure our content is accurate and current by reading our. Kosoglou T, Rocci ML Jr, Vlasses PH. The efficacy of tricyclic antidepressants can decrease when coadministered with BACTRIM. It's a type of hemolytic anemia. Sulfite sensitivity is seen more frequently in asthmatic than in non-asthmatic people. If youre allergic to any of the ingredients, ask for a different ink or avoid getting a tattoo altogether. Call your doctor for medical advice about side effects. Int J Med Toxicol. Bactrim vs. Keflex for Bacterial Infections: Differences - RxList In the literature, three cases of hyperkalemia in elderly patients have been reported after concomitant intake of BACTRIM and an angiotensin converting enzyme inhibitor. 1. 2013;3:43. Rapidly growing mycobacteria have emerged as a cause of tattoo-associated cutaneous infection in recent years. Before Safrin S, Lee BL, Sande MA. Serious and fatal adverse reactions including gasping syndrome can occur in neonates and low birth weight infants treated with benzyl alcohol-preserved formulations in infusion solutions, including BACTRIM. sores in the infected area, filled with pus or fluid. information highlighted below and resubmit the form. Eveleth R. (2012). Tell your doctor if you have diarrhea that is watery or bloody. 2001;4(2):16. However, for those who question absolutely everything, like myself, my tattoo is looking and doing good. Skin and soft tissue infections. Some epidemiologic studies suggest that exposure to BACTRIM during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular abnormalities, urinary tract defects, oral clefts, and club foot (see Human Data). Aquaphor is a product that tattoo artists often recommend to be used on new tattoos during aftercare. But its not clear if completely avoiding all legumes is actually necessary. In these cases, you might require more intensive, long-term treatment. These antibiotics are typically used to treat skin or urinary tract infections. It is possible that you are getting a Methicillin-Resistant Staphylococcus aureus from tattoos. Available for Android and iOS devices. The usual adult dosage of Bactrim DS is 1 tablet every 12 hours, or 2 Bactrim tablets every 12 hours. You have to notify your physician prescribing you Bactrim of the reality of planning or taking on taking seizure medicines, diuretics, methotrexate, blood slimmers, or ACE inhibitors. Tattoo-associated nontuberculous mycobacterial skin infections multiple states, 2011-2012. AIDS patients may not tolerate or respond to BACTRIM in the same manner as non-AIDS patients. Others only trigger problems in specific types of G6PD deficiency. Severe cases of thrombocytopenia that are fatal or life threatening have been reported. Cough, shortness of breath, and pulmonary infiltrates are hypersensitivity reactions of the respiratory tract that have been reported in association with sulfonamide treatment. I was starting to panic. Hematologic changes indicative of folic acid deficiency may occur in elderly patients. Staph bacteria, especially methicillin-resistant Staphylococcus aureus (MRSA), can also get into your bloodstream and internal organs. Bactrim (sulfamethoxazole and trimethoprim) DS is a combination of two antibiotics used to treat urinary tract infections, acute otitis media, bronchitis, Shigellosis, Pneumocystis pneumonia, traveler's diarrhea, methicillin-resistant Staphylococcus aureus (MRSA), and other bacterial infections susceptible to this antibiotic. Tell your doctor if you become pregnant. Clostridioides difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including BACTRIM, and may range in severity from mild diarrhea to fatal colitis. Observations of leukocytes obtained from patients treated with sulfamethoxazole and trimethoprim revealed no chromosomal abnormalities. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. In severe cases of infection, antibiotic treatments may last for weeks or months. Not suitable for pregnant or breastfeeding women or infants less than two months of age. These steady-state levels were achieved after three days of drug administration. Seek urgent medical advice if an unexplained cough, shortness of breath, sore throat, fever, muscle or joint pain, paleness or yellowing of the skin, or diarrhea develops. Think before you ink: Are tattoos safe? The gasping syndrome is characterized by central nervous system depression, metabolic acidosis, and gasping respirations. Copyright 2023 by RxList Inc. An Internet Brands company. May not be suitable for some people including those with kidney or liver disease, folate deficiency (the elderly, chronic alcoholics, and people taking anticonvulsants are at risk of folate deficiency), glucose-6-phosphate deficiency, porphyria, severe allergies, thyroid dysfunction, or bronchial asthma. Verywell Health's content is for informational and educational purposes only. The percent of dose excreted in urine over a 12-hour period following the intravenous administration of the first dose of 240 mg of trimethoprim and 1200 mg of sulfamethoxazole on day 1 ranged from 17% to 42.4% as free trimethoprim; 7% to 12.7% as free sulfamethoxazole; and 36.7% to 56% as total (free plus the N4-acetylated metabolite) sulfamethoxazole. Continue reading, Septra, Septra DS, Sulfatrim, Cotrim, Sulfatrim Pediatric. Nov 1973;128 (Suppl): S657-S663. Ditch the Waiting Room With Online Birth Control, The 11 Best Numbing Creams for Piercings of 2023. To make sure you can safely take Bactrim, tell your doctor if you have ever had: an electrolyte imbalance (such as low blood sodium or high potassium); porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or. Naphthalene is a vapor (gas) given off by these products. Last medically reviewed on June 10, 2021. However, the dose is usually not more than 1600 mg of sulfamethoxazole and 320 mg of trimethoprim per day. In in vitro Comet, micronucleus and chromosomal damage assays using cultured human lymphocytes, trimethoprim was positive. Depending on the reason you're taking the medication, it might not be wise to get tattooed, or it might just require shorter sessions. See your doctor if you experience one or more of the following: A staph infection is one type of infection you might get with a tattoo. The good news? The patient was treated with a 2-month course of oral trimethoprim-sulfamethoxazole (160mg/800mg twice daily) and ciprofloxacin (250 mg twice daily), with clinical improvement at follow up after three weeks of the antibiotic regimen. This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. impetigo (a honey-crusted rash) See your doctor immediately . doi:10.1136/adc.85.5.411. Sulfamethoxazole and trimethoprim combination is best taken with a full glass (8 ounces) of water. The overall prevalence of sulfite sensitivity in the general population is unknown. Following repeated intravenous administration of the same dose at 8-hour intervals, the mean plasma concentrations just prior to and immediately after each infusion at steady state were 5.6 0.6 g/mL and 8.8 0.9 g/mL for trimethoprim and 70.6 7.3 g/mL and 105.6 10.9 g/mL for sulfamethoxazole. This is one of the major risks you should be aware of before getting a new piercing or tattoo. All rights reserved. ive missed three doses. If your tissue has died due to the infection (necrosis), surgery may be needed to remove it. BACTRIM contains propylene glycol as a solvent (40% v/v). Ramakrishnan K, et al. Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Bactrim contains 400 mg sulfamethoxazole and 80 mg trimethoprim, while Bactrim DS contains 800 mg sulfamethoxazole and 160 mg trimethoprim. Bactrim belongs to the class of medicines known as antibiotics. If anything it will simply make it less likely for you to get an infection or anything like that. Trimethoprim increases the plasma concentrations of procainamide and its active N-acetyl metabolite (NAPA) when trimethoprim and procainamide are coadministered. They both are antibiotics used to treat a variety of bacterial infections. sores in the infected area, filled with pus or fluid. What drugs should be avoided with a sulfa allergy? Your doctor may take a swab of the area or lance a pus pocket (if one is present) to see what bacteria or virus is causing the infection. Studies in pregnant rabbits showed increased fetal loss at approximately 6 times the human dose on a body surface area basis (see Animal Data). All rights reserved. Monitor patients for hematologic toxicity. The length of treatment may vary from 3 days to 14 days. How long does it take for a boil to heal while taking Bactrim? Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. doctor said i should try for 7 days if i can but 6 if it looks healed could work. In those concurrently receiving certain diuretics, primarily thiazides, an increased incidence of thrombocytopenia with purpura has been reported. Pyrexia, hematuria and crystalluria may be noted. Other over-the-counter pain relievers like acetaminophen or ibuprofen don't cause issues with G6PD. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Ann Intern Med. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. (2016). Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Many people with G6PD deficiency don't experience any symptoms at all on a daily basis. You should also see a doctor if you experience uncomfortable itching around the tattooed area or if the area is oozing pus or fluid. Aspirin is often used to treat pain or inflammation. It belongs to the class of medications known as sulfonamide antibiotics. Causes and Treatment of Drug-Induced Hemolytic Anemia, Uses, Side Effects, and Procedure of a Bilirubin Test, When Iron Deficiency Anemia Is Not What It Appears to Be, How to Keep Yourself Safe Without a Spleen, The Difference Between Sulfa and Sulfite Allergies, Sulfite Allergy Overview and What to Avoid, Glucose-6-phosphate dehydrogenase deficiency, Rasburicase-induced hemolytic anemia in an adolescent with unknown glucose-6-phosphate dehydrogenase deficiency, Aspirin safety in glucose-6-phosphate dehydrogenase deficiency patients with acute coronary syndrome undergoing percutaneous coronary intervention, Henna causes life threatening haemolysis in glucose-6-phosphate dehydrogenase deficiency, Sulfa drugs, including Septra and Bactrim. It is in no way related to Penicillin. You should not use Bactrim if you are allergic to sulfamethoxazole or trimethoprim, or if you have: kidney disease that is not being treated or monitored; anemia (low red blood cells) caused by folic acid deficiency; a history of low blood platelets after taking trimethoprim or any sulfa drug; or. The free forms of trimethoprim and sulfamethoxazole are considered to be the therapeutically active forms. U.S. National Library ofMedicine. Some epidemiologic studies suggest that exposure to BACTRIM during pregnancy may be associated with an increased risk of congenital malformations, particularly neural tube defects, cardiovascular malformations, urinary tract defects, oral clefts, and club foot. Effective concentrations of both sulfamethoxazole and trimethoprim are reached in the gastrointestinal tract, urinary tract, lungs, mouth, middle ear, and vagina. Skin and Soft Tissue Infections | AAFP Glucose-6-phosphate dehydrogenase (G6PD)deficiency is a genetic condition that can be passed down from parents to their children. Monitor for the total daily intake of propylene glycol from all sources and for acid-base disturbances. Review/update the Each 5 mL should be added to 125 mL of 5% dextrose in water. When prescribing BACTRIM in pediatric patients consider the combined daily metabolic load of benzyl alcohol from all sources including BACTRIM (BACTRIM contains 10 mg of benzyl alcohol per mL) and other drugs containing benzyl alcohol. Centers for Disease Control and Prevention. Once you're off the medication, wait six months to a year for it to be out of your system, and then it's safe for you to get inked. Bactrim will not treat a viral infection (flu or a common cold). Discover the health risks associated with tattoos and piercings, tips for having a safe procedure, and, New research highlights the lack of oversight and regulation regarding the production of tattoo ink in the US and suggests some ingredients may carry, After getting a new tattoo, the outer layer of skin will typically appear healed within 2 to 3 weeks. Even when a client is HIV-positive, or has hepatitis, an artist isn't necessarily going to turn them away. Bactrim Side Effects: Common, Severe, Long Term - Drugs.com There are reported cases of henna . Keep well hydrated with fluids to avoid the development of crystals in the urine or kidney stones. The most common symptom of a tattoo infection is a rash or red, bumpy skin around the area of the tattoo. The mean maximum serum trimethoprim concentration was higher and mean renal clearance of trimethoprim was lower in geriatric subjects compared with younger subjects [see CLINICAL PHARMACOLOGY]. If you are a Mayo Clinic patient, this could If you stop taking this medicine too soon, your symptoms may return. 3. The following infusion systems have been tested and found satisfactory: unit-dose glass containers; unit-dose polyvinyl chloride and polyolefin containers. Kluger N. Contraindications for tattooing. Dont rub it dry this can damage the skin. DOI: Mekaru S. (2011). I was unable to cut grass or do anything at all other than force myself to work each day. The antibacterial effects of Bactrim persist for at least 12 hours. Aquaphor is a skin care staple for many people who have dry, chapped skin or lips. And, unfortunately, it wouldn't be the artist's fault. However, rasburicase can trigger red blood cell breakdown in people with G6PD deficiency. Brand names: Bactrim, Bactrim DS Tattoo dry healing is an acceptable part of a tattoo aftercare routine as long as you follow all other aftercare instructions closely. You should also see a doctor if a rash or swelling lasts for more than a week. The trimethoprim component of BACTRIM may cause hyperkalemia when administered to patients with underlying disorders of potassium metabolism, with renal insufficiency or when given concomitantly with drugs known to induce hyperkalemia, such as angiotensin converting enzyme inhibitors. Acute cellulitis and erysipelas in adults: Treatment. Children 2 months of age and olderDose is based on body weight and must be determined by your doctor. May lower blood sugar levels in people without diabetes. Anti-Rejection Drugs:If you have had an organ transplant and/or are on anti-rejection medication, getting a tattoo might not be in your best interest. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Discontinue BACTRIM if a significant reduction in the count of any formed blood element is noted. Bactrim (sulfamethoxazole and trimethoprim) DS is a combination of two antibiotics used to treat urinary tract infections, acute otitis media, bronchitis, Shigellosis, Pneumocystis pneumonia, traveler's diarrhea, methicillin-resistant Staphylococcus aureus (MRSA), and other bacterial infections susceptible to this antibiotic. Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by binding to and reversibly inhibiting the required enzyme, dihydrofolate reductase. Boyer EW, Stork C, Wang RY. Treatment failure and excess mortality were observed when BACTRIM was used concomitantly with leucovorin for the treatment of HIV positive patients with Pneumocystis jirovecii pneumonia in a randomized placebo controlled trial.4 Avoid coadministration of BACTRIM and leucovorin during treatment of Pneumocystis jirovecii pneumonia. Some people recommend removing all legumes (such as beans, peas, lentils, or peanuts) from your diet. People with G6PD deficiency can tolerate most antibiotics. official website and that any information you provide is encrypted Unauthorized use of these marks is strictly prohibited. Rx only. Trimethoprim, component of BACTRIM, has been noted to impair phenylalanine metabolism, but this is of no significance in phenylketonuric patients on appropriate dietary restriction. 7 Things You Should Avoid If You Have G6PD Deficiency - Verywell Health Can I get a tattoo if I am on certain medications or have certain From Healthy to Barely Functioning After Taking Bactrim and Keflex Both trimethoprim and sulfamethoxazole distribute to sputum and vaginal fluid; trimethoprim also distributes to bronchial secretions, and both pass the placental barrier and are excreted in breast milk. In rare cases of infection, surgery may be required. Arthur C Huntley MD, California Digital Library. Adults1 tablet (DS tablet) of 800 milligrams (mg) of sulfamethoxazole and 160 mg of trimethoprim, 2 tablets of 400 mg of sulfamethoxazole and 80 mg of trimethoprim, or 4 teaspoonfuls or 20 milliliters (mL) of oral liquid every 12 hours for 14 days. Instruct patients to maintain an adequate fluid intake in order to prevent crystalluria and stone formation. The artist will appreciate knowing so they can be on their guard, and maybe take extra precautions if necessary. If your infection was caused by MRSA bacteria, antibiotics may not be beneficial. Antivir Ther. These studies are further limited by recall, selection, and information biases, and by limited generalizability of their findings. The .gov means its official. Universal precautions for preventing transmission of bloodborne infections. If the artist decides that they cannot, in good conscience, proceed with the tattoo or piercing, it's because they don't want you to get hurt. Nitrofurantoin and dapsone are additional antibiotics to avoid. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. sharing sensitive information, make sure youre on a federal Primaquine is a medicine used to treat or prevent malaria. Can I Dry-Heal a Tattoo Instead of Keeping It Moisturized? In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2% to 4% and 15% to 20%, respectively. This chemical can trigger hemolysis in those with G6PD deficiency. The following side effects may get better over time as your body gets used to the medication. If you have a condition like these, it's understandable to worry that disclosing it to your artist might result in being refused service. Hypersensitivity and Other Fatal Reactions [see, Hepatitis (including cholestatic jaundice and hepatic necrosis), Elevation of serum transaminase and bilirubin, Sulfonamides bear certain chemical similarities to some goitrogens, diuretics (acetazolamide and the thiazides) and oral hypoglycemic agents (cross-sensitivity may exist with these agents), Diuresis and hypoglycemia (have occurred in patients receiving sulfonamides), Known hypersensitivity to trimethoprim or sulfonamides [see, History of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides [see, Patients with documented megaloblastic anemia due to folate deficiency [see, Pediatric patients less than two months of age [see, Severe renal insufficiency when renal function status cannot be monitored [see, Concomitant administration with dofetilide. The following in vitro data are available, but their clinical significance is unknown. What to Do If Your New Tattoo Gets Infected - Good Housekeeping While we understand if you're not 100% comfortable disclosing medical information to your tattoo artist, you should know why it matters in the first place. Cookie Notice Oct 1994;170(4):912-7. Make sure that all items that touch your skin have been properly sterilized. BACTRIM is contraindicated in pediatric patients younger than two months of age because of the potential risk of bilirubin displacement and kernicterus [see CONTRAINDICATIONS]. Therefore, BACTRIM will not prevent sequelae such as rheumatic fever. This medicine will not work for colds, flu, or other virus infections. Close monitoring of serum potassium is warranted in these patients. Appropriate dosage adjustments should be made for patients with impaired kidney function and duration of use should be as short as possible to minimize risks of undesired reactions [see DOSAGE AND ADMINISTRATION]. Sometimes after starting treatment with antibiotics, patients can develop watery and bloody stools (with or without stomach cramps and fever) even as late as two or more months after having taken the last dose of the antibiotic. In in vitro and in vivo tests in animal species, sulfamethoxazole/trimethoprim did not damage chromosomes. Advertising revenue supports our not-for-profit mission. The following adverse reactions have been identified during post-approval use of BACTRIM. Symptom relief is often seen within 3 days of starting treatment. MedlinePlus. Updated September 6, 2016. Amber Yates, MD, is a board-certified pediatric hematologist and a practicing physician at Baylor College of Medicine. Under these circumstances the solution should be mixed just prior to use and should be administered within 2 hours. Mayo Clinic College of Medicine and Science, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Graduate Medical Education, Mayo Clinic School of Continuous Professional Development, Mayo Clinic on Incontinence - Mayo Clinic Press, NEW Mayo Clinic on High Blood Pressure - Mayo Clinic Press, Mayo Clinic on Hearing and Balance - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Financial Assistance Documents Minnesota, Sulfamethoxazole And Trimethoprim (Oral Route). Bethesda, MD 20894, Web Policies She has been an amateur artist as a hobby since grade school, and served a 12 month tattoo apprenticeship in a tattoo studio. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Avoid coadministration of BACTRIM and leucovorin during treatment of Pneumocystis jirovecii pneumonia [see WARNINGS AND PRECAUTIONS]. If MRSA causes an abscess, your doctor may drain it instead of giving you antibiotics. 2018;11(11):CD009435. Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis carinii pneumonia. You may be having an allergic reaction to the ink. In the literature, a single case of toxic delirium has been reported after concomitant intake of BACTRIM and amantadine (an OCT2 substrate). the unsubscribe link in the e-mail. Dont scratch or pick at the skin. You may need more frequent check-ups or medical tests if you also use medicine to treat depression, diabetes, seizures, or HIV. But certain medications and foods can increase the rate of red blood cell breakdown and trigger anemia. What's the Difference Between a Rook Piercing and a Faux Rook Piercing, Anyway? Bactrim is an effective combination antibiotic; however, it may not be suitable for those with kidney or liver disease or folate deficiency. There have been reports of marked but reversible nephrotoxicity with coadministration of BACTRIM and cyclosporine in renal transplant recipients. sulfamethoxazole and trimethoprim DS (double strength) tablets and tablets USP. After diluting with 5% dextrose in water, the solution should not be refrigerated and should be used within 6 hours. Antibiotics: Disclose all antibiotics to your tattoo artist, and discuss whether or not it's safe to proceed. (2017). Excretion of trimethoprim and sulfamethoxazole is primarily by the kidneys through both glomerular filtration and tubular secretion. Clinical studies of BACTRIM did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. This is given in equally divided doses two times a day for 3 days a week on consecutive days (eg, Monday, Tuesday, Wednesday). If youre experiencing an infection, treatment depends on the cause. Can I Work Out With a New Piercing or Tattoo? Read our, Prescription Medications to Disclose Before Getting a Tattoo. Unable to load your collection due to an error, Unable to load your delegates due to an error.