Below are commonly used dosages, but the dosage you receive will be determined by your doctor. As you age, your BMD is reduced, and this may increase your risk for osteoporosis. Some people who take Prolia develop severe bone, joint, or muscle pain. Some side effects of Prolia may go away on their own within a few days or weeks after starting treatment. These articles might help: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. This could include having: Before taking Prolia, share your dental history with your doctor. Prolia was the right choice for me because it worked for me and it was 1 shot every 6 months. If you have serious side effects from Prolia, call your doctor right away. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. They may give you tips on managing a body weight thats healthy for you. Your doctor will order blood tests to check your level before you start using Prolia and regularly during your treatment. Other side effects may continue for as long as you receive the medication, but they can often be relieved with other treatments. Learn how to increase or maintain bone density here. If your Prolia treatment is stopped, talk to your doctor about other medicine that Some people have developed unusual fractures in their thigh bone. For women with osteoporosis after menopause at high risk for fracture. This means your bones may be weaker than usual. You can use the study as a second opinion to make health care decisions. They can also include swelling of your tongue, mouth, or throat, which can cause trouble breathing. Serious side effects from Prolia can occur, but they arent common. Your doctor or another healthcare professional will inject Prolia under the skin in one of the following areas: Prolia doses are given as an injection by healthcare professionals once every 6 months. If youre concerned about weight gain with Prolia, talk with your doctor. Calcium and calcium supplements: Achieving the right Serious skin infections may occur, but are uncommon If you have more questions about what to expect with dental procedures while youre taking Prolia, talk with your doctor or dentist. Most Medicare plans and other insurance plans cover Prolia. Talk with your doctor before starting Prolia treatment. Your dentist may have you use a chlorhexidine mouth rinse before and after surgery to reduce your risk for jaw-related side effects. Your doctor will recommend the dosage of Prolia thats right for you. in your skin, lower stomach area (abdomen), bladder, or ear may happen. Heres a short list of some of the mild side effects that Prolia can cause. Because these reports happened after the studies, it isnt known for sure whether Prolia caused hair loss, or if it was due to another reason. Follow your doctor's instructions. If your pain becomes severe, your doctor may recommend other treatment options to replace Prolia. Your doctor can also help you decide if the benefits of Prolia treatment outweigh your risks of side effects. you Below, we answer some common questions about taking Prolia. * Approximation only. Any advice? (Biologic medications are made from living organisms.). But if you think youre having a medical emergency, call 911 or your local emergency number. Check with your doctor if you have more questions about these drugs. Terms of Use. It is important to check supplement labels to ensure that the product meets United States Pharmacopeia (USP) standards. But if you look at D3 supplements online, youll see that most commercial supplements have higher doses usually either 1,000, 2,000, 5,000 or 10,000 IU. It is often used in osteoporosis. Below are answers to some commonly asked questions about Prolia. Calcium High cholesterol levels can be a side effect of Prolia. As with most drugs, Prolia can cause an allergic reaction in some people. Prolia can cause certain side effects, some of which are more common than others. Other studies have examined the risk of damage to jaw tissue with the use of bisphosphonates, one type of medication commonly used to treat osteoporosis. Instead, your doctor may recommend that you make certain changes to your diet, such as increasing your calcium and vitamin D intake. Results may vary. kidney disease (or if you are on dialysis); a weak immune system (caused by disease or by using certain medicines); hypoparathyroidism (decreased functioning of the parathyroid glands); any condition that makes it hard for your body to absorb nutrients from food (malabsorption); if you are scheduled for a dental procedure; if you cannot take daily calcium and vitamin D; or. Theyll discuss with you other treatments to help prevent bone loss. RA is an autoimmune condition in which your immune system attacks your joints. With osteoporosis, your bones become porous, meaning there are large holes within your bone tissue. Common side effects of this osteoporosis treatment injection include muscle, joint, and back pain. They can also happen if you have certain conditions or if you take certain medications. Do not share this medicine with another person, even if they have the same symptoms you have. What are some frequently asked questions about Prolia? You may need to go to the hospital for treatment. After your treatment with Prolia is stopped, or if you skip or delay taking a dose, your risk for breaking bones, including bones in your spine, is increased. Musculoskeletal pain from Prolia is mild or manageable for most people. Call your doctor for medical advice about side effects. Factors to consider include those in the list below. Prolia improves bone mass and increases bone mineral density. Theyll discuss with you other treatments to help protect you from fractures and bone loss. You may have questions about Prolia and your treatment plan. This makes your bones weak and increases your risk for bone fractures or breaks. Prolia isnt known to cause any harmful interactions with alcohol. It strengthens your bones by stopping certain bone cells called osteoclasts from breaking down your bones. A severe jawbone problem called osteonecrosis has rarely been reported with Prolia. Prolia may be used off-label for RA, if you have a high risk for bone fractures. How long will the side effects of Prolia last? This medicine is only given in a clinic, doctor's office, or other health care setting and will not be stored at home. Call your doctor for medical advice about side effects. Get the treatment that fits your lifestyle, Stay informed with courtesy reminders, recipes and so much more. Keep in mind that side effects of a drug can depend on: Additionally, you may experience different side effects from those listed below based on the condition youre treating with Prolia. It blocks the effects of certain bone cells called osteoclasts in breaking down bone tissue. But if your symptoms are serious and you think youre having a medical emergency, immediately call 911 or your local emergency number. Youll likely receive Prolia long term if you and your doctor decide that the drug is effective and safe for you. They may also suggest exercises to help improve your bone strength and lower your risk for fractures and osteoporosis. Before you start Prolia treatment, talk with your doctor about how long Prolias side effects may last. It is important not to miss your dose. This is because its not known if Prolia is safe to receive while breastfeeding. Some research has shown that alcohol consumption may increase your risk of osteoporosis, a bone fracture or impaired healing after a fracture. Do not share this medicine with others. Stopping some drugs leads to withdrawal symptoms because your body is used to the drug and needs it for you to feel normal. Store in the original container away from heat and light. It can have some side effects, but these may depend on who uses it. If you develop hypocalcemia, your doctor will typically have you stop using Prolia. Talk with your doctor about the risks of using this drug during pregnancy. Mild side effects of Prolia that have been reported include: Mild side effects of many drugs may go away within a few days or a few weeks. Its important to tell your doctor if you have serious or ongoing side effects. Its possible that some of Prolias side effects may be long term, but theyre rare. Dietary calcium is considered safe, but too much calcium in the form of supplements might have some health risks. Call your doctor right away if you have an allergic reaction to Prolia. Learn more about the unique risk factors for osteoporosis in, Osteoporosis weakens bones, which leads to breaks in the hips, wrists, and spine. Learn strategies you can use today. Youll receive 60 mg/mL of Prolia once every 6 months. Use of the terms female and male in this article refers to sex assigned at birth. If youre pregnant or breastfeeding, or considering either, talk with your doctor. To learn more about this side effect, see Side effect specifics below. Bone density decreases with time, and some people have a risk of developing weak or brittle bones. They may be able to help you identify the cause. So be sure to talk with your doctor about any past or upcoming surgery before starting treatment with the drug. If youve been diagnosed with osteoporosis, your doctor may discuss Prolia with you. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. These include osteonecrosis of the jawbone. We avoid using tertiary references. If youre using Prolia and feel fatigued despite getting enough sleep, talk with your doctor. Low blood calcium level. A healthcare provider will give you this injection in a hospital or clinic. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. Learn how estrogen affects bone health and how you can protect yourself from bone loss, Osteoporosis is more common in women than men, but it affects millions of men every year. Serious infections may occur during treatment with Prolia. You may also want to do some research on your own. If you notice any tooth or jaw pain, or sensitivity while using Prolia, talk with your doctor or dentist right away. Tingling wasnt specifically reported as a side effect of Prolia in clinical trials. Visit www.fda.gov/medwatch, orcall1-800-FDA-1088. Your risk for having more than 1 broken bone in your spine is increased if you have already had a broken bone in your spine. Your doctor can provide more information to you about the benefits and risks of using Prolia for your condition. Pay special attention to your dental hygiene. And if you have osteoporosis, falling could increase your risk of fractures. If you have any questions about Prolias side effects, talk with your doctor. Mild side effects can occur with Prolia use. Brush and floss your teeth as directed. Your doctor can help you decide which drug is better for your needs. * For more information about this side effect, see Side effect specifics below. What should be considered before taking Prolia? Last medically reviewed on November 29, 2022. Continue reading, Yes, Prolia does appear to weaken your immune system. Ask your doctor about your own risk. Treating any mouth or dental problems early is the best way to help prevent serious dental complications. These problems may include: Your risk for mouth-related side effects may be higher if you have problems with your teeth. (To learn more, see the Side effect specifics section above.). Before starting Prolia treatment, talk with your doctor about any tooth procedures you have scheduled. Prolia is meant to be used in combination with calcium and vitamin D supplements. Youll receive Prolia doses from a healthcare professional. such as inflammation of your skin (dermatitis), rash, and eczema have been reported. Denosumab is contraindicated in women with hypocalcaemia. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Continue reading. More than half of American adults take an herbal or dietary supplement, and many more use over-the-counter or prescription drugs to manage maladies ranging from the occasional headache to chronic health conditions or mood disorders.. For many, it is part of their daily routine. Follow your doctor's instructions about any restrictions on food, beverages, or activity. But theyre each effective in treating osteoporosis and preventing bone loss. Mild side effects that have been reported with Prolia include: These side effects may be temporary, lasting a few days or weeks. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. All subjects in the clinical trials of Prolia received 800mg of calcium and Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problem. As mentioned above, Prolia contains the active drug denosumab. But before taking Prolia, be sure to tell your doctor about all medications you take (including prescription and over-the-counter types).
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